Download scientific diagram | The differences between the MARCO and SR-A1 structures (By Figdraw). MARCO has a longer collagenous domain and does not have the α-helical coiled-coil domain that is present in SR-A1; MARCO directly binds ligands via the SRCR domain, whereas SR-A1 primarily binds ligands through its collagenous domain from publication: The application of MARCO for immune regulation and treatment | Macrophage receptor with collagen structure (MARCO) is a member of scavenger receptor class A (SR-A) and shares structural and functional similarities with SR-A1. In recent years, many studies have shown that MARCO can trigger an immune response and has therapeutic potential | Immunochemistry, Immunotherapy and B Cells | ResearchGate, the professional network for scientists.
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